Cetirizine Dihydrochloride impurity D

Cetirizine Dihydrochloride impurity D - Names and Identifiers

Name	1,4-Bis[(4-chlorophenyl)phenylmethyl]piperazine
Synonyms	Cetirizine IMpurity D Cetirizine Dihydrochloride impurity D 1,4-Bis[(4-chlorophenyl)phenylmethyl]piperazine Piperazine, 1,4-bis[(4- chlorophenyl)phenylMethyl]- 1,4-Bis[(4-chlorophenyl)phenylmethyl]piperazine DiHCl 1,4-Bis[alpha-(4-chlorophenyl)benzyl]piperazine dihydrochloride 1,4-BIS[(4-CHLOROPHENYL)PHENYLMETHYL]PIPERAZINE DIHYDROCHLORIDE
CAS	346451-15-8

Cetirizine Dihydrochloride impurity D - Physico-chemical Properties

Molecular Formula	C30H28Cl2N2
Molar Mass	487.46
Density	1.228±0.06 g/cm3(Predicted)
Melting Point	>180°C (dec.)
Boling Point	270-275 °C(Press: 1 Torr)
Solubility	Chloroform (Slightly, Heated, Sonicated), DMSO (Slightly, Heated), Methanol (Sli
Appearance	Solid
Color	White
pKa	5.85±0.10(Predicted)
Storage Condition	Hygroscopic, Refrigerator, Under inert atmosphere
Stability	Hygroscopic

Cetirizine Dihydrochloride impurity D - Reference Information

biological activity

Cetirizine impure D is an Impurity of Cetirizine. Cetirizine is a second-generation antihistamine. Cetirizine is a specific, orally active H1 receptor antagonist. Cetirizine marks anti-allergic properties and inhibits eosinophil chemotaxis during anaphylaxis.

Last Update：2024-04-09 20:52:54